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Gene Information
Gene ID:64946
Symbol:CENPH
Full Name:centromere protein H
Alias:NNF1|PMF1
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5p15.2
Physical Location:68521130-68541939 on NC_000005.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D5S647  66282906
Region:66282906-76193808
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_022909.3NP_075060.1NC_000005.8 range: 68521130..68541939
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000776kinetochoreCellular ComponentNAS (11092768)
GO:0005634nucleusCellular ComponentIDA (11092768)
GO:0005694chromosomeCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIPI (11092768)
GO:0043515kinetochore bindingMolecular FunctionIDA (11092768)
GO:0051383kinetochore organization and biogenesisBiological ProcessTAS (11092768)
Other Database Cross Links
NCBI Entrez Gene:64946
HGNC:17268
Ensembl:ENSG00000153044
MIM:605607
HPRD:12029
HuGE Navigator:64946
dbSNP:CENPH
GeneCard:CENPH
AceView:CENPH