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Gene Information
Gene ID:65061
Symbol:PFTK2
Full Name:PFTAIRE protein kinase 2
Alias:ALS2CR7
Organism:Homo sapiens (Human)
Chromosome:2
Genetic Location:2q33.2
Physical Location:202379442-202466510 on NC_000002.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D2S117  195326948
Region:195326948-216757195
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_139158.1NP_631897.1NC_000002.10 range: 202379442..202466510
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0000287magnesium ion bindingMolecular FunctionIEA
GO:0004693cyclin-dependent protein kinase activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (17353931)
GO:0005524ATP bindingMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:65061
HGNC:14434
Ensembl:ENSG00000138395
MIM:
HPRD:12449
HuGE Navigator:65061
dbSNP:PFTK2
GeneCard:PFTK2
AceView:PFTK2