ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SLC3A2

Full Name:

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

Alias:

4F2|4F2HC|4T2HC|CD98|CD98HC|MDU1|NACAE

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q13

Physical Location:

62380093-62412928 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0042470	melanosome	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	NAS (3476959)
GO:0016020	membrane	Cellular Component	IEA
GO:0009986	cell surface	Cellular Component	IEP (12493773)
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0043169	cation binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	ISS
GO:0005515	protein binding	Molecular Function	IPI (10506149\|10631289)
GO:0005432	calcium:sodium antiporter activity	Molecular Function	TAS (10673541)
GO:0006816	calcium ion transport	Biological Process	NAS (3036867)
GO:0006810	transport	Biological Process	IEA
GO:0005975	carbohydrate metabolic process	Biological Process	IEA
GO:0015827	tryptophan transport	Biological Process	ISS
GO:0016049	cell growth	Biological Process	NAS (3476959)
GO:0006865	amino acid transport	Biological Process	TAS (10673541)