ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SLC22A3

Full Name:

solute carrier family 22 (extraneuronal monoamine transporter), member 3

Alias:

EMT|EMTH|OCT3

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

6q26-q27

Physical Location:

160689414-160796003 on NC_000006.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID	No. of Publications	Phenotype
SLC22A3	1	Alcoholism

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_021977.2	NP_068812.1	NC_000006.10 range: 160689414..160796003

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005624	membrane fraction	Cellular Component	TAS (9933568)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (9933568)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005215	transporter activity	Molecular Function	IEA
GO:0015075	ion transmembrane transporter activity	Molecular Function	IEA
GO:0015651	quaternary ammonium group transmembrane transporter activity	Molecular Function	IDA (10966924)
GO:0006811	ion transport	Biological Process	IEA
GO:0015697	quaternary ammonium group transport	Biological Process	IDA (10966924)