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Gene Information
Gene ID:6588
Symbol:SLN
Full Name:sarcolipin
Alias:MGC12301|MGC125854|MGC125855
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11q22-q23
Physical Location:107083310-107087996 on NC_000011.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:U96094
Fold Change:1.7, 1.7
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Information
Original ID1:SLN
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003063.2NP_003054.1NC_000011.8 range: 107083310..107087996, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentTAS (9367679)
GO:0033017sarcoplasmic reticulum membraneCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionISS
GO:0030234enzyme regulator activityMolecular FunctionIEA
GO:0006810transportBiological ProcessTAS (9367679)
GO:0051924regulation of calcium ion transportBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:6588
HGNC:11089
Ensembl:ENSG00000170290
MIM:602203
HPRD:03729
HuGE Navigator:6588
dbSNP:SLN
GeneCard:SLN
AceView:SLN