ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ufc1

Full Name:

ubiquitin-fold modifier conjugating enzyme 1

Alias:

1110021H02Rik|AA062310|ESTM29

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H3|1 93.0 cM

Physical Location:

173218694-173225112 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 51506 Symbol (Name): UFC1 (ubiquitin-fold modifier conjugating enzyme 1)

Ortholog Status:

The human GeneID 51506 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

1110021H02Rik

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw1	Acute Alcohol Withdrawal	1	96	172.3-176.5 (Mb)	5.6	3.00E-07	Significant	PARC
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025388.2	NP_079664.1	NC_000067.5 range: 173218694..173225112, complement

Gene Ontology (GO) Annotation