ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Klf15

Full Name:

Kruppel-like factor 15

Alias:

1810013I09Rik|AV048136|AW494632|CKLF|KKLF

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

6 D1

Physical Location:

90412619-90425202 on NC_000072.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 28999 Symbol (Name): KLF15 (Kruppel-like factor 15)

Ortholog Status:

The human GeneID 28999 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AI852911
Fold Change:		6.5, 1.7, 2.8, 1.6
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_023184.3	NP_075673.1	NC_000072.5 range: 90412619..90425202

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (12097321)
GO:0005622	intracellular	Cellular Component	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0003676	nucleic acid binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12097321)
GO:0003700	transcription factor activity	Molecular Function	IDA (12097321)
GO:0003677	DNA binding	Molecular Function	ISS (15820306)
GO:0003677	DNA binding	Molecular Function	IDA (12097321)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0015758	glucose transport	Biological Process	IDA (12097321)
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA (12097321)