ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tbcb

Full Name:

tubulin folding cofactor B

Alias:

2410007D12Rik|AU041393|CG22|CKAPI|Ckap1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

7 B1

Physical Location:

31009156-31016804 on NC_000073.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1155 Symbol (Name): TBCB (tubulin folding cofactor B)

Ortholog Status:

The human GeneID 1155 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Ckap1

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025548.3	NP_079824.2	NC_000073.5 range: 31009156..31016804, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005856	cytoskeleton	Cellular Component	RCA (12466851)
GO:0005874	microtubule	Cellular Component	IEA
GO:0015630	microtubule cytoskeleton	Cellular Component	RCA (12466851)
GO:0006457	protein folding	Biological Process	RCA (12466851)
GO:0007017	microtubule-based process	Biological Process	RCA (12466851)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007399	nervous system development	Biological Process	IEA
GO:0030154	cell differentiation	Biological Process	IEA