ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SPOCK1

Full Name:

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1

Alias:

FLJ37170|SPOCK|TESTICAN|TIC1

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

5q31

Physical Location:

136338885-136862916 on NC_000005.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004598.3	NP_004589.1	NC_000005.8 range: 136338885..136862916, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	NR
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0006928	cell motility	Biological Process	TAS (8389704)
GO:0007155	cell adhesion	Biological Process	TAS (8389704)
GO:0007275	multicellular organismal development	Biological Process	TAS (8389704)
GO:0007399	nervous system development	Biological Process	TAS (9181134)
GO:0008283	cell proliferation	Biological Process	TAS (8389704)