ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SPP1

Full Name:

secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)

Alias:

BNSP|BSPI|ETA-1|MGC110940|OPN

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

4q21-q25

Physical Location:

89115825-89123586 on NC_000004.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Information

Original ID1:

SPP1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation