ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SPR

Full Name:

sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

2p14-p12

Physical Location:

72968055-72972793 on NC_000002.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

SPR

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003124.4	NP_003115.1	NC_000002.10 range: 72968055..72972793

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0004033	aldo-keto reductase activity	Molecular Function	TAS (1883349)
GO:0004757	sepiapterin reductase activity	Molecular Function	TAS (9792819)
GO:0005488	binding	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0050661	NADP binding	Molecular Function	TAS (1883349)
GO:0006729	tetrahydrobiopterin biosynthetic process	Biological Process	TAS (1883349)
GO:0006809	nitric oxide biosynthetic process	Biological Process	IDA (15197144)
GO:0055114	oxidation reduction	Biological Process	TAS (1883349)