ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

BRCA2

Full Name:

breast cancer 2, early onset

Alias:

BRCC2|FACD|FAD|FAD1|FANCB|FANCD|FANCD1

Organism:

Homo sapiens (Human)

Chromosome:

13

Genetic Location:

13q12.3

Physical Location:

31787616-31871808 on NC_000013.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

BRCA2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000059.3	NP_000050.2	NC_000013.9 range: 31787616..31871808

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0033593	BRCA2-MAGE-D1 complex	Cellular Component	IDA (15930293)
GO:0030141	secretory granule	Cellular Component	IDA (8589722)
GO:0005813	centrosome	Cellular Component	IDA (17286961)
GO:0005654	nucleoplasm	Cellular Component	EXP (12606939)
GO:0005634	nucleus	Cellular Component	IDA (9560268\|9774970\|17286961)
GO:0005515	protein binding	Molecular Function	IPI (9774970\|10373512\|11597317\|12242698\|15930293\|15967112\|16099937\|16275750\|17515903)
GO:0004402	histone acetyltransferase activity	Molecular Function	IDA (9824164)
GO:0003697	single-stranded DNA binding	Molecular Function	IEA
GO:0043015	gamma-tubulin binding	Molecular Function	IPI (17286961)
GO:0016563	transcription activator activity	Molecular Function	IDA (9619837)
GO:0033595	response to genistein	Biological Process	IDA (16434996)
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	Biological Process	IDA (15930293)
GO:0043627	response to estrogen stimulus	Biological Process	IDA (8895509)
GO:0000724	double-strand break repair via homologous recombination	Biological Process	IEA
GO:0033205	cytokinesis during cell cycle	Biological Process	IDA (17286961)
GO:0007090	regulation of S phase of mitotic cell cycle	Biological Process	NAS (9774970)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IC (9619837)
GO:0006310	DNA recombination	Biological Process	IEA
GO:0006289	nucleotide-excision repair	Biological Process	IMP (16845393)
GO:0051298	centrosome duplication	Biological Process	IDA (17286961)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000139618

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: