ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ADAM17

Full Name:

ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme)

Alias:

CD156b|MGC71942|TACE|cSVP

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

2p25

Physical Location:

9546842-9613367 on NC_000002.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ADAM17

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003183.4	NP_003174.3	NC_000002.10 range: 9546842..9613367, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (9574564)
GO:0016020	membrane	Cellular Component	IEA
GO:0004222	metalloendopeptidase activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (10527948)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006508	proteolysis	Biological Process	IEA
GO:0007219	Notch signaling pathway	Biological Process	IEA
GO:0007267	cell-cell signaling	Biological Process	TAS (9034190)