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Gene Information
Gene ID:6879
Symbol:TAF7
Full Name:TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
Alias:TAF2F|TAFII55
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q31
Physical Location:140678240-140680534 on NC_000005.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:X97999
Fold Change:1.4, 1.4
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_005642.2NP_005633.2NC_000005.8 range: 140678240..140680534, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0005669transcription factor TFIID complexCellular ComponentIDA (14580349)
GO:0003713transcription coactivator activityMolecular FunctionTAS (7824954)
GO:0005515protein bindingMolecular FunctionTAS (7824954)
GO:0016251general RNA polymerase II transcription factor activityMolecular FunctionTAS (7824954)
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:6879
HGNC:11541
Ensembl:ENSG00000178913
MIM:600573
HPRD:07196
HuGE Navigator:6879
dbSNP:TAF7
GeneCard:TAF7
AceView:TAF7