ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TAF7

Full Name:

TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa

Alias:

TAF2F|TAFII55

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

5q31

Physical Location:

140678240-140680534 on NC_000005.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		X97999
Fold Change:		1.4, 1.4
Note:		Differential Expression on the cDNA array (two fold changes are from two case groups)

Dataset Information

Name:		11141048
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:		RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005642.2	NP_005633.2	NC_000005.8 range: 140678240..140680534, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005669	transcription factor TFIID complex	Cellular Component	IDA (14580349)
GO:0003713	transcription coactivator activity	Molecular Function	TAS (7824954)
GO:0005515	protein binding	Molecular Function	TAS (7824954)
GO:0016251	general RNA polymerase II transcription factor activity	Molecular Function	TAS (7824954)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA