ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Rasl11b

Full Name:

RAS-like, family 11, member B

Alias:

1190017B18Rik|MGC103217

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

5 D

Physical Location:

74591350-74595501 on NC_000071.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 65997 Symbol (Name): RASL11B (RAS-like, family 11, member B)

Ortholog Status:

The human GeneID 65997 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Rasl11b

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_026878.1	NP_081154.1	NC_000071.5 range: 74591350..74595501

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005525	GTP binding	Molecular Function	IEA
GO:0007264	small GTPase mediated signal transduction	Biological Process	RCA (12466851)