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Gene Information
Gene ID:6910
Symbol:TBX5
Full Name:T-box 5
Alias:HOS
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12q24.1
Physical Location:113276117-113330629 on NC_000012.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:TBX5
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000192.3NP_000183.2NC_000012.10 range: 113276117..113330629, complement
NM_080717.2NP_542448.1NC_000012.10 range: 113276117..113330629, complement
NM_080718.1NP_542449.1NC_000012.10 range: 113276117..113330629, complement
NM_181486.1NP_852259.1NC_000012.10 range: 113276117..113330629, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIDA (14519429)
GO:0005634nucleusCellular ComponentIDA (12237100|12499378|14519429)
GO:0003700transcription factor activityMolecular FunctionIDA (11431700|12499378|16332960)
GO:0005515protein bindingMolecular FunctionIPI (11431700|12499378|12845333|16332960)
GO:0003702RNA polymerase II transcription factor activityMolecular FunctionIDA (12845333)
GO:0003700transcription factor activityMolecular FunctionIEA
GO:0043565sequence-specific DNA bindingMolecular FunctionIDA (11431700|12499378)
GO:0035117embryonic arm morphogenesisBiological ProcessIMP (16183809)
GO:0035136forelimb morphogenesisBiological ProcessIMP (8988164|8988165)
GO:0045893positive regulation of transcription, DNA-dependentBiological ProcessIDA (11431700|12499378|12845333)
GO:0051891positive regulation of cardioblast differentiationBiological ProcessIDA (11431700)
GO:0060039pericardium developmentBiological ProcessIDA (15138308)
GO:0030336negative regulation of cell migrationBiological ProcessIDA (15138308)
GO:0030326embryonic limb morphogenesisBiological ProcessIMP (8988164)
GO:0007507heart developmentBiological ProcessNAS (12845333)
GO:0007507heart developmentBiological ProcessIMP (8988165|16183809)
GO:0007507heart developmentBiological ProcessIDA (15138308)
GO:0007275multicellular organismal developmentBiological ProcessIEA
GO:0007267cell-cell signalingBiological ProcessIDA (11161571)
GO:0006917induction of apoptosisBiological ProcessIDA (12237100)
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
GO:0060044negative regulation of cardiac muscle cell proliferationBiological ProcessIDA (11161571)
Other Database Cross Links
NCBI Entrez Gene:6910
HGNC:11604
Ensembl:ENSG00000089225
MIM:601620
HPRD:03372
HuGE Navigator:6910
dbSNP:TBX5
GeneCard:TBX5
AceView:TBX5