ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TBX3

Full Name:

T-box 3 (ulnar mammary syndrome)

Alias:

TBX3-ISO|UMS|XHL

Organism:

Homo sapiens (Human)

Chromosome:

12

Genetic Location:

12q24.1

Physical Location:

113592441-113606351 on NC_000012.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TBX3

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005996.3	NP_005987.3	NC_000012.10 range: 113592441..113606351, complement
NM_016569.3	NP_057653.3	NC_000012.10 range: 113592441..113606351, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (11689487)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0003702	RNA polymerase II transcription factor activity	Molecular Function	TAS (9207801)
GO:0016565	general transcriptional repressor activity	Molecular Function	IDA (11689487)
GO:0043565	sequence-specific DNA binding	Molecular Function	IDA (11689487)
GO:0001501	skeletal development	Biological Process	IMP (9207801)
GO:0035117	embryonic arm morphogenesis	Biological Process	IMP (12116211)
GO:0035136	forelimb morphogenesis	Biological Process	IDA (9207801)
GO:0042733	embryonic digit morphogenesis	Biological Process	IMP (9207801\|12116211)
GO:0045662	negative regulation of myoblast differentiation	Biological Process	IDA (12032820)
GO:0045787	positive regulation of cell cycle	Biological Process	IDA (12032820)
GO:0045892	negative regulation of transcription, DNA-dependent	Biological Process	IDA (10468588\|11689487)
GO:0046884	follicle-stimulating hormone secretion	Biological Process	IMP (12116211)
GO:0032275	luteinizing hormone secretion	Biological Process	IMP (12116211)
GO:0030879	mammary gland development	Biological Process	IMP (12116211)
GO:0030540	female genitalia development	Biological Process	IMP (12116211)
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	TAS (9207801)
GO:0006916	anti-apoptosis	Biological Process	IDA (12032820)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007569	cell aging	Biological Process	IDA (11689487\|11748239)
GO:0008284	positive regulation of cell proliferation	Biological Process	IDA (11689487\|11748239\|12032820)
GO:0008595	determination of anterior/posterior axis, embryo	Biological Process	IMP (9207801)
GO:0009887	organ morphogenesis	Biological Process	IDA (9207801)
GO:0030539	male genitalia development	Biological Process	IMP (12116211)
GO:0048332	mesoderm morphogenesis	Biological Process	IMP (9207801)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000135111

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: