ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

BTK

Full Name:

Bruton agammaglobulinemia tyrosine kinase

Alias:

AGMX1|AT|ATK|BPK|IMD1|MGC126261|MGC126262|PSCTK1|XLA

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

Xq21.33-q22

Physical Location:

100491097-100527837 on NC_000023.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

BTK

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000061.1	NP_000052.1	NC_000023.9 range: 100491097..100527837, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045121	membrane raft	Cellular Component	IDA (15046600)
GO:0016020	membrane	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	TAS (15046600)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	TAS (11913944)
GO:0004715	non-membrane spanning protein tyrosine kinase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (9012831\|9571151\|11788586)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0019722	calcium-mediated signaling	Biological Process	TAS (15046600)
GO:0008624	induction of apoptosis by extracellular signals	Biological Process	TAS (8688094)
GO:0007498	mesoderm development	Biological Process	TAS (8013627)
GO:0007242	intracellular signaling cascade	Biological Process	TAS (11913944)
GO:0006468	protein amino acid phosphorylation	Biological Process	TAS (11913944)
GO:0007242	intracellular signaling cascade	Biological Process	IEA