ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TDG

Full Name:

thymine-DNA glycosylase

Organism:

Homo sapiens (Human)

Chromosome:

12

Genetic Location:

12q24.1

Physical Location:

102883746-102906785 on NC_000012.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TDG

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003211.3	NP_003202.3	NC_000012.10 range: 102883746..102906785

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005654	nucleoplasm	Cellular Component	EXP (10583946)
GO:0005654	nucleoplasm	Cellular Component	TAS (9489705)
GO:0003684	damaged DNA binding	Molecular Function	TAS (9489705)
GO:0005515	protein binding	Molecular Function	IPI (14667819)
GO:0030983	mismatched DNA binding	Molecular Function	IEA
GO:0019104	DNA N-glycosylase activity	Molecular Function	EXP (10583946)
GO:0016798	hydrolase activity, acting on glycosyl bonds	Molecular Function	IEA
GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	Molecular Function	TAS (8662714)
GO:0008152	metabolic process	Biological Process	IEA
GO:0006298	mismatch repair	Biological Process	IEA
GO:0006284	base-excision repair	Biological Process	TAS (9489705)
GO:0045008	depyrimidination	Biological Process	EXP (10583946\|11937636)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000139372

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: