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Gene Information
Gene ID:7074
Symbol:TIAM1
Full Name:T-cell lymphoma invasion and metastasis 1
Alias:FLJ36302
Organism:Homo sapiens (Human)
Chromosome:21
Genetic Location:21q22.1|21q22.11
Physical Location:31412606-31853160 on NC_000021.7, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AL533992
Fold Change:0.66
P Value:9.00E-03
Tissue:Nucleus accumbens
Dataset Information
Name:15816859
Method:Microarray
Tissue:Prefrontal cortex and nucleus accumbens
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003253.2NP_003244.2NC_000021.7 range: 31412606..31853160, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005057receptor signaling protein activityMolecular FunctionIEA
GO:0005085guanyl-nucleotide exchange factor activityMolecular FunctionIEA
GO:0005089Rho guanyl-nucleotide exchange factor activityMolecular FunctionIEA
GO:0005089Rho guanyl-nucleotide exchange factor activityMolecular FunctionTAS (10835422)
GO:0005515protein bindingMolecular FunctionIEA
GO:0007165signal transductionBiological ProcessIEA
GO:0007242intracellular signaling cascadeBiological ProcessIEA
GO:0035023regulation of Rho protein signal transductionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:7074
HGNC:11805
Ensembl:ENSG00000156299
MIM:600687
HPRD:02820
HuGE Navigator:7074
dbSNP:TIAM1
GeneCard:TIAM1
AceView:TIAM1