ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TLR2

Full Name:

toll-like receptor 2

Alias:

CD282|TIL4

Organism:

Homo sapiens (Human)

Chromosome:

4

Genetic Location:

4q32

Physical Location:

154824890-154846692 on NC_000004.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TLR2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003264.3	NP_003255.2	NC_000004.10 range: 154824890..154846692

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0009986	cell surface	Cellular Component	IDA (12443841)
GO:0005886	plasma membrane	Cellular Component	EXP (14625308\|16024789)
GO:0005886	plasma membrane	Cellular Component	TAS (9435236)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (9435236)
GO:0001875	lipopolysaccharide receptor activity	Molecular Function	TAS (11518816)
GO:0042834	peptidoglycan binding	Molecular Function	IDA (11986301)
GO:0051076	Gram-positive bacterial binding	Molecular Function	IDA (11521063)
GO:0005515	protein binding	Molecular Function	IPI (10854325\|15657077)
GO:0004888	transmembrane receptor activity	Molecular Function	IEA
GO:0006917	induction of apoptosis	Biological Process	TAS (10426996)
GO:0007165	signal transduction	Biological Process	TAS (11044375)
GO:0007249	I-kappaB kinase/NF-kappaB cascade	Biological Process	EXP (15276183)
GO:0045087	innate immune response	Biological Process	IEA
GO:0006954	inflammatory response	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000137462

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: