ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TPO

Full Name:

thyroid peroxidase

Alias:

MSA|TPX

Organism:

Homo sapiens (Human)

Chromosome:

2

Genetic Location:

2p25

Physical Location:

1396241-1525501 on NC_000002.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TPO

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000547.3	NP_000538.3	NC_000002.10 range: 1396241..1525501
NM_175719.1	NP_783650.1	NC_000002.10 range: 1396241..1525501
NM_175721.1	NP_783652.1	NC_000002.10 range: 1396241..1525501
NM_175722.1	NP_783653.1	NC_000002.10 range: 1396241..1525501

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0005887	integral to plasma membrane	Cellular Component	TAS (2548579)
GO:0005575	cellular_component	Cellular Component	ND
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0004601	peroxidase activity	Molecular Function	NAS (1401057)
GO:0004601	peroxidase activity	Molecular Function	IEA
GO:0020037	heme binding	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0009053	electron donor activity	Molecular Function	IEA
GO:0004447	iodide peroxidase activity	Molecular Function	IEA
GO:0042446	hormone biosynthetic process	Biological Process	IEA
GO:0006979	response to oxidative stress	Biological Process	IEA
GO:0006590	thyroid hormone generation	Biological Process	NR
GO:0006590	thyroid hormone generation	Biological Process	NAS (1401057)
GO:0042744	hydrogen peroxide catabolic process	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000115705

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: