ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TRAF6

Full Name:

TNF receptor-associated factor 6

Alias:

MGC:3310|RNF85

Organism:

Homo sapiens (Human)

Chromosome:

11

Genetic Location:

11p12

Physical Location:

36467301-36488397 on NC_000011.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TRAF6

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004620.2	NP_004611.1	NC_000011.8 range: 36467301..36488397, complement
NM_145803.1	NP_665802.1	NC_000011.8 range: 36467301..36488397, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	EXP (9162092\|9744859\|10066798\|10465784\|12138165\|12609980\|15125833)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (11244088\|11397809\|11751921\|15125833)
GO:0004871	signal transducer activity	Molecular Function	IEP (12761501)
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	IDA (15125833)
GO:0050852	T cell receptor signaling pathway	Biological Process	IMP (15125833)
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process	IEP (12761501)
GO:0042981	regulation of apoptosis	Biological Process	IEA
GO:0000209	protein polyubiquitination	Biological Process	IDA (15125833)
GO:0032743	positive regulation of interleukin-2 production	Biological Process	IMP (15125833)
GO:0007250	activation of NF-kappaB-inducing kinase activity	Biological Process	IMP (15125833)
GO:0007165	signal transduction	Biological Process	IEA
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0002726	positive regulation of T cell cytokine production	Biological Process	IMP (15125833)
GO:0050870	positive regulation of T cell activation	Biological Process	IC (15125833)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000175104

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: