ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TUBA4A

Full Name:

tubulin, alpha 4a

Alias:

FLJ30169|H2-ALPHA|TUBA1

Organism:

Homo sapiens (Human)

Chromosome:

2

Genetic Location:

2q35

Physical Location:

219823244-219826881 on NC_000002.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		W33064
Fold Change:		0.63
P Value:		3.00E-04
Tissue:		Nucleus accumbens

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_006000.1	NP_005991.1	NC_000002.10 range: 219823244..219826881, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005874	microtubule	Cellular Component	IEA
GO:0043234	protein complex	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0003924	GTPase activity	Molecular Function	IEA
GO:0005198	structural molecule activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (14697242)
GO:0005525	GTP binding	Molecular Function	IEA
GO:0007018	microtubule-based movement	Biological Process	IEA
GO:0051258	protein polymerization	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000127824

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: