ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TYMS

Full Name:

thymidylate synthetase

Alias:

HsT422|MGC88736|TMS|TS|TSase

Organism:

Homo sapiens (Human)

Chromosome:

18

Genetic Location:

18p11.32

Physical Location:

647650-663491 on NC_000018.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TYMS

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001071.2	NP_001062.1	NC_000018.8 range: 647650..663491

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005829	cytosol	Cellular Component	EXP (2656695)
GO:0004799	thymidylate synthase activity	Molecular Function	EXP (2656695)
GO:0004799	thymidylate synthase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0008168	methyltransferase activity	Molecular Function	IEA
GO:0009165	nucleotide biosynthetic process	Biological Process	IEA
GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	Biological Process	TAS (2987839)
GO:0006281	DNA repair	Biological Process	NAS (15504738)
GO:0006260	DNA replication	Biological Process	NAS (15504738)
GO:0006231	dTMP biosynthetic process	Biological Process	IEA
GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	Biological Process	TAS (2987839)
GO:0048015	phosphoinositide-mediated signaling	Biological Process	NAS (15504738)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000176890

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: