ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

TYR

Full Name:

tyrosinase (oculocutaneous albinism IA)

Alias:

OCA1A|OCAIA|SHEP3

Organism:

Homo sapiens (Human)

Chromosome:

11

Genetic Location:

11q14-q21

Physical Location:

88550687-88668574 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

TYR

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000372.4	NP_000363.1	NC_000011.8 range: 88550687..88668574

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IDA (11092760)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0033162	melanosome membrane	Cellular Component	IEA
GO:0005798	Golgi-associated vesicle	Cellular Component	TAS (10823941)
GO:0005764	lysosome	Cellular Component	TAS (11092760)
GO:0005737	cytoplasm	Cellular Component	IDA (11092760)
GO:0016020	membrane	Cellular Component	IEA
GO:0042803	protein homodimerization activity	Molecular Function	ISS
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0046982	protein heterodimerization activity	Molecular Function	ISS
GO:0004497	monooxygenase activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	ISS
GO:0005507	copper ion binding	Molecular Function	IMP (11092760)
GO:0004503	monophenol monooxygenase activity	Molecular Function	IDA (11092760)
GO:0007605	sensory perception of sound	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA
GO:0006726	eye pigment biosynthetic process	Biological Process	TAS (7704033)
GO:0006583	melanin biosynthetic process from tyrosine	Biological Process	TAS (7704033)
GO:0007601	visual perception	Biological Process	TAS (7704033)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000077498

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: