ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

UBE2V2

Full Name:

ubiquitin-conjugating enzyme E2 variant 2

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

8q11.21

Physical Location:

49083547-49137006 on NC_000008.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003350.2	NP_003341.1	NC_000008.9 range: 49083547..49137006

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0031372	UBC13-MMS2 complex	Cellular Component	IDA (16129784)
GO:0005634	nucleus	Cellular Component	IDA (16129784)
GO:0005737	cytoplasm	Cellular Component	TAS (16129784)
GO:0005515	protein binding	Molecular Function	IPI (11473255\|16786304)
GO:0019787	small conjugating protein ligase activity	Molecular Function	IEA
GO:0000209	protein polyubiquitination	Biological Process	TAS (10089880)
GO:0008283	cell proliferation	Biological Process	TAS (9418904)
GO:0006282	regulation of DNA repair	Biological Process	TAS (10089880)
GO:0000729	DNA double-strand break processing	Biological Process	IMP (17349954)
GO:0051246	regulation of protein metabolic process	Biological Process	IEA