ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

UBP1

Full Name:

upstream binding protein 1 (LBP-1a)

Alias:

DKFZp686L1745|LBP-1B|LBP-1a|LBP1A|LBP1B

Organism:

Homo sapiens (Human)

Chromosome:

3

Genetic Location:

3p22.3

Physical Location:

33404834-33456873 on NC_000003.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		H63585
Fold Change:		0.68
P Value:		0.05
Tissue:		Prefrontal cortex

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_014517.4	NP_055332.3	NC_000003.10 range: 33404834..33456873, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	TAS (8114710)
GO:0003700	transcription factor activity	Molecular Function	TAS (8114710)
GO:0003714	transcription corepressor activity	Molecular Function	TAS (8114710)
GO:0016566	specific transcriptional repressor activity	Molecular Function	TAS (8114710)
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	TAS (8114710)
GO:0016481	negative regulation of transcription	Biological Process	TAS (8114710)
GO:0019079	viral genome replication	Biological Process	TAS (8114710)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000153560

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: