ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Errfi1

Full Name:

ERBB receptor feedback inhibitor 1

Alias:

1300002F13Rik|AI788755|Mig-6|Mig6|RALT

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 E1

Physical Location:

150229199-150242988 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 54206 Symbol (Name): ERRFI1 (ERBB receptor feedback inhibitor 1)

Ortholog Status:

The human GeneID 54206 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AI853531
Fold Change:		2.0, 1.6, 1.6, 1.4
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_133753.1	NP_598514.1	NC_000070.5 range: 150229199..150242988

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	ISO
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (15102471)
GO:0031098	stress-activated protein kinase signaling pathway	Biological Process	ISO