ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

VDR

Full Name:

vitamin D (1,25- dihydroxyvitamin D3) receptor

Alias:

NR1I1

Organism:

Homo sapiens (Human)

Chromosome:

12

Genetic Location:

12q13.11

Physical Location:

46521586-46585080 on NC_000012.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

VDR

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

Original ID	No. of Publications	Phenotype
VDR	1	Alcoholism

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000376.2	NP_000367.1	NC_000012.10 range: 46521586..46585080, complement
NM_001017535.1	NP_001017535.1	NC_000012.10 range: 46521586..46585080, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0008434	vitamin D3 receptor activity	Molecular Function	TAS (9070272)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (10866662)
GO:0003707	steroid hormone receptor activity	Molecular Function	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0016481	negative regulation of transcription	Biological Process	IDA (11891224)
GO:0007165	signal transduction	Biological Process	TAS (2849209)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000111424

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: