ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

VEGFA

Full Name:

vascular endothelial growth factor A

Alias:

MGC70609|VEGF|VEGF-A|VPF

Organism:

Homo sapiens (Human)

Chromosome:

6

Genetic Location:

6p12

Physical Location:

43845930-43862201 on NC_000006.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

VEGFA

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001025366.1	NP_001020537.2	NC_000006.10 range: 43845930..43862201
NM_001025367.1	NP_001020538.2	NC_000006.10 range: 43845930..43862201
NM_001025368.1	NP_001020539.2	NC_000006.10 range: 43845930..43862201
NM_001025369.1	NP_001020540.2	NC_000006.10 range: 43845930..43862201
NM_001025370.1	NP_001020541.2	NC_000006.10 range: 43845930..43862201
NM_001033756.1	NP_001028928.1	NC_000006.10 range: 43845930..43862201
NM_003376.4	NP_003367.4	NC_000006.10 range: 43845930..43862201

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0009986	cell surface	Cellular Component	IDA (17470632)
GO:0016020	membrane	Cellular Component	IEA
GO:0031093	platelet alpha granule lumen	Cellular Component	EXP (9684805)
GO:0005615	extracellular space	Cellular Component	TAS (9202027)
GO:0005615	extracellular space	Cellular Component	IDA (16490744)
GO:0005578	proteinaceous extracellular matrix	Cellular Component	NAS (14570917)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	EXP (9684805)
GO:0005515	protein binding	Molecular Function	IPI (17222790)
GO:0050840	extracellular matrix binding	Molecular Function	NAS (14570917)
GO:0008201	heparin binding	Molecular Function	IDA (15001987)
GO:0008083	growth factor activity	Molecular Function	NAS (11016853)
GO:0008083	growth factor activity	Molecular Function	IEA
GO:0042803	protein homodimerization activity	Molecular Function	NAS (12127077)
GO:0043498	cell surface binding	Molecular Function	IDA (17470632)
GO:0005161	platelet-derived growth factor receptor binding	Molecular Function	IPI (17470632)
GO:0005172	vascular endothelial growth factor receptor binding	Molecular Function	TAS (1711045)
GO:0043066	negative regulation of apoptosis	Biological Process	IMP (10066377\|11461089)
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	Biological Process	NAS (10066377)
GO:0030335	positive regulation of cell migration	Biological Process	IDA (17470632)
GO:0048008	platelet-derived growth factor receptor signaling pathway	Biological Process	IDA (17470632)
GO:0008284	positive regulation of cell proliferation	Biological Process	TAS (9202027)
GO:0001525	angiogenesis	Biological Process	NAS (15351965)
GO:0001570	vasculogenesis	Biological Process	TAS (15015550)
GO:0001666	response to hypoxia	Biological Process	IDA (16490744)
GO:0007165	signal transduction	Biological Process	TAS (1711045)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007399	nervous system development	Biological Process	TAS (15351965)
GO:0001525	angiogenesis	Biological Process	IDA (11427521)
GO:0008283	cell proliferation	Biological Process	IEA
GO:0050930	induction of positive chemotaxis	Biological Process	NAS (12744932)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000112715

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: