| Gene Information |
| Gene ID: | | 7428 |
| Symbol: | | VHL |
| Full Name: | | von Hippel-Lindau tumor suppressor |
| Alias: | | HRCA1|RCA1|VHL1 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 3 |
| Genetic Location: | | 3p26-p25 |
| Physical Location: | | 10158318-10168761 on NC_000003.10 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0005829 | cytosol | Cellular Component | TAS (7604013) | |
| GO:0005783 | endoplasmic reticulum | Cellular Component | NAS (12169691) | |
| GO:0005739 | mitochondrion | Cellular Component | NAS (12169691) | |
| GO:0005737 | cytoplasm | Cellular Component | IEA | |
| GO:0005634 | nucleus | Cellular Component | TAS (7604013) | |
| GO:0008134 | transcription factor binding | Molecular Function | TAS (7660122) | |
| GO:0045786 | negative regulation of cell cycle | Biological Process | IEA | |
| GO:0045597 | positive regulation of cell differentiation | Biological Process | NAS (12169691) | |
| GO:0045449 | regulation of transcription | Biological Process | IMP (15824735) | |
| GO:0016567 | protein ubiquitination | Biological Process | IMP (12169691) | |
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | Biological Process | TAS (7660122) | |
| GO:0008285 | negative regulation of cell proliferation | Biological Process | TAS (7660130) | |
| GO:0006950 | response to stress | Biological Process | NAS (12169691) | |
| GO:0006916 | anti-apoptosis | Biological Process | NAS (12169691) | |
| GO:0006508 | proteolysis | Biological Process | TAS (10353251) | |
| GO:0000902 | cell morphogenesis | Biological Process | NAS (12169691) | |
| GO:0050821 | protein stabilization | Biological Process | NAS (12169691) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 7428 |
| HGNC: | | 12687 |
| Ensembl: | | ENSG00000134086 |
| MIM: | | 608537 |
| HPRD: | | 01905 |
| HuGE Navigator: | | 7428 |
| dbSNP: | | VHL |
| GeneCard: | | VHL |
| AceView: | | VHL |
