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Gene Information
Gene ID:753
Symbol:C18orf1
Full Name:chromosome 18 open reading frame 1
Organism:Homo sapiens (Human)
Chromosome:18
Genetic Location:18p11.2
Physical Location:13208794-13642752 on NC_000018.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D18S53  11482730
Region:9482730-13482730
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001003674.1NP_001003674.1NC_000018.8 range: 13208794..13642752
NM_001003675.1NP_001003675.1NC_000018.8 range: 13208794..13642752
NM_004338.2NP_004329.1NC_000018.8 range: 13208794..13642752
NM_181481.2NP_852146.1NC_000018.8 range: 13208794..13642752
NM_181482.2NP_852147.1NC_000018.8 range: 13208794..13642752
NM_181483.2NP_852148.1NC_000018.8 range: 13208794..13642752
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentNAS (9479497)
GO:0003674molecular_functionMolecular FunctionND
GO:0008150biological_processBiological ProcessND
Other Database Cross Links
NCBI Entrez Gene:753
HGNC:1224
Ensembl:ENSG00000168675
MIM:606571
HPRD:07358
HuGE Navigator:753
dbSNP:C18orf1
GeneCard:C18orf1
AceView:C18orf1