ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ZAP70

Full Name:

zeta-chain (TCR) associated protein kinase 70kDa

Alias:

FLJ17670|FLJ17679|SRK|STD|TZK|ZAP-70

Organism:

Homo sapiens (Human)

Chromosome:

2

Genetic Location:

2q12

Physical Location:

97696462-97722754 on NC_000002.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ZAP70

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001079.3	NP_001070.2	NC_000002.10 range: 97696462..97722754
NM_207519.1	NP_997402.1	NC_000002.10 range: 97696462..97722754

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	TAS (12359715)
GO:0005829	cytosol	Cellular Component	EXP (11048639\|17652306)
GO:0042101	T cell receptor complex	Cellular Component	IDA (8176201)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0004715	non-membrane spanning protein tyrosine kinase activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (7528772\|11891219\|12359715\|12646565)
GO:0005524	ATP binding	Molecular Function	NAS (1423621)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0045059	positive thymic T cell selection	Biological Process	IDA (7630421)
GO:0007243	protein kinase cascade	Biological Process	NAS (1423621)
GO:0007165	signal transduction	Biological Process	IEA
GO:0006955	immune response	Biological Process	IDA (1423621)
GO:0006468	protein amino acid phosphorylation	Biological Process	NAS (1423621)
GO:0045582	positive regulation of T cell differentiation	Biological Process	IDA (7630421)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000115085

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: