ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ZNF24

Full Name:

zinc finger protein 24

Alias:

KOX17|RSG-A|ZNF191|ZSCAN3|Zfp191

Organism:

Homo sapiens (Human)

Chromosome:

18

Genetic Location:

18q12

Physical Location:

31169956-31178404 on NC_000018.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AA134770
Fold Change:		0.67
P Value:		1.00E-03
Tissue:		Prefrontal cortex

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_006965.2	NP_008896.2	NC_000018.8 range: 31169956..31178404, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IC (10585455)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (16169070)
GO:0008270	zinc ion binding	Molecular Function	NAS (10585455)
GO:0016564	transcription repressor activity	Molecular Function	IDA (10585455)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0016481	negative regulation of transcription	Biological Process	IDA (10585455)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000172466

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: