ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

2700078E11Rik

Full Name:

RIKEN cDNA 2700078E11 gene

Alias:

2810417M16Rik|9830127L17Rik|AI450346|D130033C15Rik

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 D3

Physical Location:

60603768-60656882 on NC_000085.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 143384 Symbol (Name): C10orf46 (chromosome 10 open reading frame 46)

Ortholog Status:

The human GeneID 143384 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

2700078E11Rik

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_030197.1	NP_084473.1	NC_000085.5 range: 60603768..60656882, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0031461	cullin-RING ubiquitin ligase complex	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IEA
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	IEA