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Gene Information
Gene ID:8079
Symbol:MLF2
Full Name:myeloid leukemia factor 2
Alias:NTN4
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12p13
Physical Location:6727422-6732529 on NC_000012.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D12S99  5434815
Region:3434815-7434815
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_005439.1NP_005430.1NC_000012.10 range: 6727422..6732529, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0005634nucleusCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIPI (17353931)
GO:0006952defense responseBiological ProcessIMP (8661158)
Other Database Cross Links
NCBI Entrez Gene:8079
HGNC:7126
Ensembl:ENSG00000089693
MIM:601401
HPRD:03238
HuGE Navigator:8079
dbSNP:MLF2
GeneCard:MLF2
AceView:MLF2