ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ITCH

Full Name:

itchy E3 ubiquitin protein ligase homolog (mouse)

Alias:

AIF4|AIP4|NAPP1|dJ468O1.1

Organism:

Homo sapiens (Human)

Chromosome:

20

Genetic Location:

20q11.22-q11.23

Physical Location:

32414744-32562857 on NC_000020.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ITCH

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_031483.4	NP_113671.3	NC_000020.9 range: 32414744..32562857

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005575	cellular_component	Cellular Component	ND
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	NAS (10940313)
GO:0005515	protein binding	Molecular Function	IPI (9647693)
GO:0016874	ligase activity	Molecular Function	IEA
GO:0006954	inflammatory response	Biological Process	NAS (9462742)
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0006511	ubiquitin-dependent protein catabolic process	Biological Process	NAS (9462742)
GO:0006464	protein modification process	Biological Process	IEA
GO:0001558	regulation of cell growth	Biological Process	NAS (9462742)
GO:0046718	entry of virus into host cell	Biological Process	TAS (12450395)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000078747

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: