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Gene Information
Gene ID:84282
Symbol:RNF135
Full Name:ring finger protein 135
Alias:L13|MGC13061
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17q11.2
Physical Location:26322081-26351052 on NC_000017.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S798  28313925
Region:26313925-30313925
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_032322.3NP_115698.3NC_000017.9 range: 26322081..26351052
NM_197939.1NP_922921.1NC_000017.9 range: 26322081..26351052
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005515protein bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:84282
HGNC:21158
Ensembl:ENSG00000181481
MIM:611358
HPRD:11506
HuGE Navigator:84282
dbSNP:RNF135
GeneCard:RNF135
AceView:RNF135