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Gene Information
Gene ID:8507
Symbol:ENC1
Full Name:ectodermal-neural cortex (with BTB-like domain)
Alias:CCL28|ENC-1|FLJ39259|KLHL35|NRPB|PIG10|TP53I10
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q12-q13.3
Physical Location:73958989-73972272 on NC_000005.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D5S647  66282906
Region:66282906-76193808
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003633.2NP_003624.1NC_000005.8 range: 73958989..73972272, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentTAS (9566959)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005856cytoskeletonCellular ComponentIEA
GO:0016363nuclear matrixCellular ComponentIEA
GO:0003779actin bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0006512ubiquitin cycleBiological ProcessIEA
GO:0007275multicellular organismal developmentBiological ProcessTAS (9566959)
GO:0007399nervous system developmentBiological ProcessTAS (9566959)
Other Database Cross Links
NCBI Entrez Gene:8507
HGNC:3345
Ensembl:ENSG00000171617
MIM:605173
HPRD:05529
HuGE Navigator:8507
dbSNP:ENC1
GeneCard:ENC1
AceView:ENC1