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Gene Information
Gene ID:8567
Symbol:MADD
Full Name:MAP-kinase activating death domain
Alias:DENN|IG20|KIAA0358|RAB3GEP
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11p11.2
Physical Location:47247534-47308157 on NC_000011.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:MADD
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003682.2NP_003673.2NC_000011.8 range: 47247534..47308157
NM_130470.1NP_569826.1NC_000011.8 range: 47247534..47308157
NM_130471.1NP_569827.1NC_000011.8 range: 47247534..47308157
NM_130472.1NP_569828.1NC_000011.8 range: 47247534..47308157
NM_130473.1NP_569829.1NC_000011.8 range: 47247534..47308157
NM_130474.1NP_569830.1NC_000011.8 range: 47247534..47308157
NM_130475.1NP_569831.1NC_000011.8 range: 47247534..47308157
NM_130476.1NP_569832.1NC_000011.8 range: 47247534..47308157
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentTAS (8988362)
GO:0016021integral to membraneCellular ComponentIDA (8988362)
GO:0005737cytoplasmCellular ComponentTAS (8988362)
GO:0017112Rab guanyl-nucleotide exchange factor activityMolecular FunctionIMP (9115275)
GO:0030295protein kinase activator activityMolecular FunctionTAS (9115275)
GO:0005515protein bindingMolecular FunctionIPI (9115275)
GO:0005123death receptor bindingMolecular FunctionTAS (9115275)
GO:0005085guanyl-nucleotide exchange factor activityMolecular FunctionIEA
GO:0042981regulation of apoptosisBiological ProcessIMP (9115275|11577081|14735464)
GO:0000187activation of MAPK activityBiological ProcessIMP (9115275)
GO:0007166cell surface receptor linked signal transductionBiological ProcessTAS (9115275)
GO:0051726regulation of cell cycleBiological ProcessIMP (14735464)
Other Database Cross Links
NCBI Entrez Gene:8567
HGNC:6766
Ensembl:ENSG00000110514
MIM:603584
HPRD:04664
HuGE Navigator:8567
dbSNP:MADD
GeneCard:MADD
AceView:MADD