ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SOCS1

Full Name:

suppressor of cytokine signaling 1

Alias:

CIS1|CISH1|JAB|SOCS-1|SSI-1|SSI1|TIP3

Organism:

Homo sapiens (Human)

Chromosome:

16

Genetic Location:

16p13.13

Physical Location:

11255774-11257539 on NC_000016.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

SOCS1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003745.1	NP_003736.1	NC_000016.8 range: 11255774..11257539, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	TAS (9202126)
GO:0004860	protein kinase inhibitor activity	Molecular Function	TAS (9202125)
GO:0005159	insulin-like growth factor receptor binding	Molecular Function	IPI (9727029)
GO:0005515	protein binding	Molecular Function	IEA
GO:0019901	protein kinase binding	Molecular Function	IPI (9727029)
GO:0001558	regulation of cell growth	Biological Process	IEA
GO:0046426	negative regulation of JAK-STAT cascade	Biological Process	NAS (9727029)
GO:0046426	negative regulation of JAK-STAT cascade	Biological Process	ISS
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	Biological Process	ISS
GO:0019221	cytokine and chemokine mediated signaling pathway	Biological Process	ISS
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0006512	ubiquitin cycle	Biological Process	IEA
GO:0001932	regulation of protein amino acid phosphorylation	Biological Process	ISS
GO:0046627	negative regulation of insulin receptor signaling pathway	Biological Process	ISS

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000185338

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: