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Gene Information
Gene ID:8651
Symbol:SOCS1
Full Name:suppressor of cytokine signaling 1
Alias:CIS1|CISH1|JAB|SOCS-1|SSI-1|SSI1|TIP3
Organism:Homo sapiens (Human)
Chromosome:16
Genetic Location:16p13.13
Physical Location:11255774-11257539 on NC_000016.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:SOCS1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003745.1NP_003736.1NC_000016.8 range: 11255774..11257539, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentTAS (9202126)
GO:0004860protein kinase inhibitor activityMolecular FunctionTAS (9202125)
GO:0005159insulin-like growth factor receptor bindingMolecular FunctionIPI (9727029)
GO:0005515protein bindingMolecular FunctionIEA
GO:0019901protein kinase bindingMolecular FunctionIPI (9727029)
GO:0001558regulation of cell growthBiological ProcessIEA
GO:0046426negative regulation of JAK-STAT cascadeBiological ProcessNAS (9727029)
GO:0046426negative regulation of JAK-STAT cascadeBiological ProcessISS
GO:0042518negative regulation of tyrosine phosphorylation of Stat3 proteinBiological ProcessISS
GO:0019221cytokine and chemokine mediated signaling pathwayBiological ProcessISS
GO:0007242intracellular signaling cascadeBiological ProcessIEA
GO:0006512ubiquitin cycleBiological ProcessIEA
GO:0001932regulation of protein amino acid phosphorylationBiological ProcessISS
GO:0046627negative regulation of insulin receptor signaling pathwayBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:8651
HGNC:19383
Ensembl:ENSG00000185338
MIM:603597
HPRD:04669
HuGE Navigator:8651
dbSNP:SOCS1
GeneCard:SOCS1
AceView:SOCS1