ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CBL

Full Name:

Cas-Br-M (murine) ecotropic retroviral transforming sequence

Alias:

C-CBL|CBL2|RNF55

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q23.3

Physical Location:

118582199-118684068 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 12402 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CBL

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005188.2	NP_005179.2	NC_000011.8 range: 118582199..118684068

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005829	cytosol	Cellular Component	EXP (8621719\|11823423\|14505571)
GO:0005886	plasma membrane	Cellular Component	IDA (15465819)
GO:0005886	plasma membrane	Cellular Component	EXP (10567358\|11894095\|12218189\|12593796\|15475003\|15962011\|16407834)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0016874	ligase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	TAS (2030914)
GO:0005515	protein binding	Molecular Function	IPI (11891219)
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	TAS (15465819)
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	EXP (12218189\|12593796\|16407834)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	TAS (15465819)
GO:0007173	epidermal growth factor receptor signaling pathway	Biological Process	TAS (15465819)
GO:0016567	protein ubiquitination	Biological Process	TAS (15465819)
GO:0048260	positive regulation of receptor-mediated endocytosis	Biological Process	TAS (15465819)