ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CBS

Full Name:

cystathionine-beta-synthase

Alias:

HIP4

Organism:

Homo sapiens (Human)

Chromosome:

21

Genetic Location:

21q22.3

Physical Location:

43346369-43369489 on NC_000021.7, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CBS

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000071.1	NP_000062.1	NC_000021.7 range: 43346369..43369489, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IDA (16780588)
GO:0004122	cystathionine beta-synthase activity	Molecular Function	TAS (9590298)
GO:0030170	pyridoxal phosphate binding	Molecular Function	IEA
GO:0016829	lyase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0008652	amino acid biosynthetic process	Biological Process	IEA
GO:0006535	cysteine biosynthetic process from serine	Biological Process	IEA
GO:0019343	cysteine biosynthetic process via cystathionine	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000160200

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: