ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

FADD

Full Name:

Fas (TNFRSF6)-associated via death domain

Alias:

GIG3|MGC8528|MORT1

Organism:

Homo sapiens (Human)

Chromosome:

11

Genetic Location:

11q13.3

Physical Location:

69726916-69731143 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

FADD

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003824.2	NP_003815.1	NC_000011.8 range: 69726916..69731143

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	NR
GO:0005829	cytosol	Cellular Component	EXP (7536190\|8681376\|9721089\|10894160\|12887920)
GO:0004871	signal transducer activity	Molecular Function	IEP (12761501)
GO:0005123	death receptor binding	Molecular Function	TAS (7538907)
GO:0042802	identical protein binding	Molecular Function	IPI (7536190)
GO:0042981	regulation of apoptosis	Biological Process	IEA
GO:0008633	activation of pro-apoptotic gene products	Biological Process	EXP (14644197)
GO:0008625	induction of apoptosis via death domain receptors	Biological Process	TAS (7538907)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	NR
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process	IEP (12761501)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000168040

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: