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Gene Information
Gene ID:8839
Symbol:WISP2
Full Name:WNT1 inducible signaling pathway protein 2
Alias:CCN5|CT58|CTGF-L
Organism:Homo sapiens (Human)
Chromosome:20
Genetic Location:20q12-q13.1
Physical Location:42777298-42789865 on NC_000020.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D20S119  43082264
Region:41082264-45082264
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003881.2NP_003872.1NC_000020.9 range: 42777298..42789865
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005625soluble fractionCellular ComponentTAS (9843955)
GO:0005515protein bindingMolecular FunctionIEA
GO:0005520insulin-like growth factor bindingMolecular FunctionIEA
GO:0001558regulation of cell growthBiological ProcessIEA
GO:0007155cell adhesionBiological ProcessIEA
GO:0007165signal transductionBiological ProcessTAS (9843955)
GO:0007267cell-cell signalingBiological ProcessTAS (9843955)
Other Database Cross Links
NCBI Entrez Gene:8839
HGNC:12770
Ensembl:ENSG00000064205
MIM:603399
HPRD:16020
HuGE Navigator:8839
dbSNP:WISP2
GeneCard:WISP2
AceView:WISP2