ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

8915

Symbol:

BCL10

Full Name:

B-cell CLL/lymphoma 10

Alias:

CARMEN|CIPER|CLAP|c-E10|mE10

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1p22

Physical Location:

85504046-85516170 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

BCL10

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_003921.3	NP_003912.1	NC_000001.9 range: 85504046..85516170, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0048471	perinuclear region of cytoplasm	Cellular Component	IDA (16127295)
GO:0046696	lipopolysaccharide receptor complex	Cellular Component	IDA (16831874)
GO:0005829	cytosol	Cellular Component	IDA (12154360)
GO:0005829	cytosol	Cellular Component	EXP (15122200\|15125833\|17468049)
GO:0005764	lysosome	Cellular Component	IDA (15082780)
GO:0005737	cytoplasm	Cellular Component	IDA (11021819\|11053425\|11278692\|15082780)
GO:0005634	nucleus	Cellular Component	IDA (16280327)
GO:0005622	intracellular	Cellular Component	IEA
GO:0032449	CBM complex	Cellular Component	NAS (15125833)
GO:0042101	T cell receptor complex	Cellular Component	IDA (12154360)
GO:0031625	ubiquitin protein ligase binding	Molecular Function	IPI (16395405)
GO:0043621	protein self-association	Molecular Function	IPI (15125833)
GO:0043422	protein kinase B binding	Molecular Function	IPI (16280327)
GO:0019209	kinase activator activity	Molecular Function	IDA (15125833)
GO:0043130	ubiquitin binding	Molecular Function	IDA (15082780)
GO:0008022	protein C-terminus binding	Molecular Function	IPI (11053425)
GO:0003713	transcription coactivator activity	Molecular Function	IDA (15207693)
GO:0051059	NF-kappaB binding	Molecular Function	IDA (16280327)
GO:0051260	protein homooligomerization	Biological Process	ISS (16831874)
GO:0051092	activation of NF-kappaB transcription factor	Biological Process	IDA (10400625\|14695475)
GO:0045087	innate immune response	Biological Process	IEP (16831874)
GO:0045416	positive regulation of interleukin-8 biosynthetic process	Biological Process	IMP (17095757)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA (15207693)
GO:0050852	T cell receptor signaling pathway	Biological Process	IDA (15125833)
GO:0001843	neural tube closure	Biological Process	ISS (11163238)
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	Biological Process	IEP (12761501)
GO:0002224	toll-like receptor signaling pathway	Biological Process	IC (16831874)
GO:0002237	response to molecule of bacterial origin	Biological Process	IEP (16831874)
GO:0002250	adaptive immune response	Biological Process	TAS (16831874)
GO:0002906	negative regulation of mature B cell apoptosis	Biological Process	IDA (15878976)
GO:0008219	cell death	Biological Process	IDA (10400625)
GO:0031398	positive regulation of protein ubiquitination	Biological Process	IDA (14695475)
GO:0032765	positive regulation of mast cell cytokine production	Biological Process	NAS (16647297)
GO:0042109	lymphotoxin A biosynthetic process	Biological Process	NAS (16647297)
GO:0042221	response to chemical stimulus	Biological Process	IDA (17095757)
GO:0042226	interleukin-6 biosynthetic process	Biological Process	NAS (16647297)
GO:0042327	positive regulation of phosphorylation	Biological Process	IDA (15125833)
GO:0042981	regulation of apoptosis	Biological Process	IEA
GO:0051260	protein homooligomerization	Biological Process	TAS (16831874)