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Gene Information
Gene ID:894
Symbol:CCND2
Full Name:cyclin D2
Alias:KIAK0002|MGC102758
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12p13
Physical Location:4253198-4284776 on NC_000012.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D12S99  5434815
Region:3434815-7434815
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001759.2NP_001750.1NC_000012.10 range: 4253198..4284776
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000307cyclin-dependent protein kinase holoenzyme complexCellular ComponentIDA (8114739)
GO:0005634nucleusCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIPI (11896535)
GO:0019901protein kinase bindingMolecular FunctionIPI (8114739)
GO:0001934positive regulation of protein amino acid phosphorylationBiological ProcessIDA (8114739)
GO:0007049cell cycleBiological ProcessIEA
GO:0045737positive regulation of cyclin-dependent protein kinase activityBiological ProcessIDA (8114739)
GO:0051301cell divisionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:894
HGNC:1583
Ensembl:ENSG00000118971
MIM:123833
HPRD:00451
HuGE Navigator:894
dbSNP:CCND2
GeneCard:CCND2
AceView:CCND2