Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:8973
Symbol:CHRNA6
Full Name:cholinergic receptor, nicotinic, alpha 6
Alias:CHNRA6
Organism:Homo sapiens (Human)
Chromosome:8
Genetic Location:8p11.21
Physical Location:42726919-42742775 on NC_000008.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:CHRNA6
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original IDNo. of PublicationsPhenotype
CHRNA61Alcoholism
CHRNA61Alcohol-Related Disorders
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_004198.2NP_004189.1NC_000008.9 range: 42726919..42742775, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045211postsynaptic membraneCellular ComponentIEA
GO:0045202synapseCellular ComponentIEA
GO:0030054cell junctionCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentIEA
GO:0005892nicotinic acetylcholine-gated receptor-channel complexCellular ComponentTAS (8906617)
GO:0016021integral to membraneCellular ComponentIEA
GO:0015464acetylcholine receptor activityMolecular FunctionTAS (8906617)
GO:0004889nicotinic acetylcholine-activated cation-selective channel activityMolecular FunctionTAS (8906617)
GO:0005230extracellular ligand-gated ion channel activityMolecular FunctionIEA
GO:0005216ion channel activityMolecular FunctionIEA
GO:0007268synaptic transmissionBiological ProcessTAS (8906617)
GO:0006811ion transportBiological ProcessIEA
GO:0007165signal transductionBiological ProcessTAS (8906617)
Other Database Cross Links
NCBI Entrez Gene:8973
HGNC:15963
Ensembl:ENSG00000147434
MIM:606888
HPRD:06056
HuGE Navigator:8973
dbSNP:CHRNA6
GeneCard:CHRNA6
AceView:CHRNA6