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Gene Information
Gene ID:90199
Symbol:WFDC8
Full Name:WAP four-disulfide core domain 8
Alias:C20orf170|WAP8|dJ461P17.1
Organism:Homo sapiens (Human)
Chromosome:20
Genetic Location:20q13.12
Physical Location:43613204-43641378 on NC_000020.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D20S119  43082264
Region:41082264-45082264
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_130896.2NP_570966.2NC_000020.9 range: 43613204..43641378, complement
NM_181510.2NP_852611.2NC_000020.9 range: 43613204..43641378, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0004867serine-type endopeptidase inhibitor activityMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:90199
HGNC:16163
Ensembl:ENSG00000158901
MIM:
HPRD:11685
HuGE Navigator:90199
dbSNP:WFDC8
GeneCard:WFDC8
AceView:WFDC8